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Comparison between Urine Protein: Creatinine Ratios of Samples Obtained from Dogs in Home and Hospital Settings.
- Source :
-
Journal of veterinary internal medicine [J Vet Intern Med] 2015 Jul-Aug; Vol. 29 (4), pp. 1029-35. Date of Electronic Publication: 2015 Jun 08. - Publication Year :
- 2015
-
Abstract
- Background: The urine protein:creatinine ratio (UPC) is used to quantify urine protein excretion and guide recommendations for monitoring and treatment of proteinuria.<br />Hypothesis/objectives: Home urine samples will have lower UPCs than hospital samples. The objectives were to compare UPCs of samples collected in each setting and to determine whether environment of sample collection might affect staging, monitoring or treatment recommendations.<br />Animals: Twenty-four client-owned dogs.<br />Methods: Prospective, nonmasked study. Clients collected a urine sample from their dog at home and a second sample was collected at the hospital. Dogs receiving corticosteroids or angiotensin-converting enzyme inhibitors were excluded, as were those with urine samples of inadequate volume, no protein on dipstick analysis, or active urine sediment. Samples were refrigerated after collection, dipstick and sediment evaluations were completed and each sample was frozen at -80°C within 12 hours. UPCs were performed on frozen samples within 2 months.<br />Results: From 81 paired samples, 57 were excluded. Of the remaining 24, 12/24 (50%) had higher hospital sample UPCs, 9/24 (38%) had identical UPCs, and 3/24 (12%) had lower hospital UPCs. The UPCs of hospital samples were higher than home samples for the total population (P = .005) and the subset with UPC > 0.5 (P = .001).<br />Conclusions: Setting and related circumstances of urine collection in dogs is associated with UPC differences; results are usually higher in hospital than in home samples. This difference has the potential to affect clinical interpretation.<br /> (© 2015 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine.)
- Subjects :
- Animals
Female
Home Care Services statistics & numerical data
Hospitals, Animal statistics & numerical data
Male
Prospective Studies
Reproducibility of Results
Urinalysis methods
Urinalysis veterinary
Urine Specimen Collection methods
Urine Specimen Collection statistics & numerical data
Creatinine urine
Dogs urine
Proteinuria urine
Urine Specimen Collection veterinary
Subjects
Details
- Language :
- English
- ISSN :
- 1939-1676
- Volume :
- 29
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Journal of veterinary internal medicine
- Publication Type :
- Academic Journal
- Accession number :
- 26059431
- Full Text :
- https://doi.org/10.1111/jvim.12836