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NDM-1-Producing Citrobacter freundii, Escherichia coli, and Acinetobacter baumannii Identified from a Single Patient in China.
- Source :
-
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2015 Aug; Vol. 59 (8), pp. 5073-7. Date of Electronic Publication: 2015 Jun 08. - Publication Year :
- 2015
-
Abstract
- We identified New Delhi metallo-β-lactamase (NDM-1)-producing Citrobacter freundii GB032, Escherichia coli GB102, and Acinetobacter baumannii GB661 in urine and stool samples from a single patient in China. Plasmid profiling and Southern blotting indicated that blaNDM-1 from GB032 and that from GB102 were likely located on the same plasmid, while blaNDM-1 from GB661 was located on a very large (>400-kb) plasmid. This case underscores the broad host range of blaNDM-1 and its potential to spread between members of the family Enterobacteriaceae and A. baumannii.<br /> (Copyright © 2015, American Society for Microbiology. All Rights Reserved.)
- Subjects :
- Acinetobacter Infections drug therapy
Acinetobacter baumannii genetics
Acinetobacter baumannii isolation & purification
Anti-Bacterial Agents therapeutic use
China
Citrobacter freundii genetics
Citrobacter freundii isolation & purification
Enterobacteriaceae Infections drug therapy
Escherichia coli genetics
Escherichia coli isolation & purification
Feces microbiology
Humans
Male
Microbial Sensitivity Tests
Middle Aged
Molecular Sequence Data
Multilocus Sequence Typing
Plasmids genetics
Plasmids isolation & purification
Urine microbiology
beta-Lactamases biosynthesis
Acinetobacter baumannii drug effects
Citrobacter freundii drug effects
Drug Resistance, Multiple, Bacterial genetics
Escherichia coli drug effects
beta-Lactamases genetics
Subjects
Details
- Language :
- English
- ISSN :
- 1098-6596
- Volume :
- 59
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Antimicrobial agents and chemotherapy
- Publication Type :
- Academic Journal
- Accession number :
- 26055374
- Full Text :
- https://doi.org/10.1128/AAC.04682-14