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Diketopiperazines and Sesquilignans from the Branches and Leaves of Claoxylon polot.
- Source :
-
Planta medica [Planta Med] 2015 Jun; Vol. 81 (9), pp. 748-53. Date of Electronic Publication: 2015 Jun 03. - Publication Year :
- 2015
-
Abstract
- Six new diketopiperazines (1-6), two new sesquilignans (7-8), and ten known compounds (9-18) were isolated from the branches and leaves of Claoxylon polot. Their structures were elucidated by extensive spectroscopic analysis. The absolute configurations of 1-3 were assigned by computational methods. Compounds 1 and 2 exhibited antiviral activity against Coxsackie B3 virus with IC50 values of 14.6 and 25.9 µM, respectively.<br /> (Georg Thieme Verlag KG Stuttgart · New York.)
- Subjects :
- Animals
Antiviral Agents isolation & purification
Antiviral Agents pharmacology
Chlorocebus aethiops
Diketopiperazines isolation & purification
Diketopiperazines pharmacology
Lignans isolation & purification
Lignans pharmacology
Molecular Structure
Plant Leaves chemistry
Vero Cells
Antiviral Agents chemistry
Diketopiperazines chemistry
Enterovirus B, Human drug effects
Euphorbiaceae chemistry
Lignans chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1439-0221
- Volume :
- 81
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Planta medica
- Publication Type :
- Academic Journal
- Accession number :
- 26039264
- Full Text :
- https://doi.org/10.1055/s-0035-1546083