Back to Search Start Over

[Tandem repeats in rodents genome and their mapping].

Authors :
Ostromyshenskii DI
Kuznetsova LS
Komissarov AS
Kartavtseva IV
Podgornaya L
Source :
Tsitologiia [Tsitologiia] 2015; Vol. 57 (2), pp. 102-10.
Publication Year :
2015

Abstract

Tandemly-repeated sequences represent a unique class of eukaryotic DNA. Their content in the genome of higher eukaryotes mounts to tens of percents. However, the evolution of this class of sequences is poorly-studied. In our paper, 62 families of Mus musculus tandem repeats are analyzed by bioinformatic methods, and 7 of them are analyzed by fluorescence in situ hybridization. It is shown that the same tandem repeat sets co-occure only in closely related species of mice. But even in such species we observe differences in localization on the chromosomes and the number of individual tandem repeats. With increasing evolutionary distance only some of the tandem repeat families remain common for different species. It is shown, that the use of a combination of bioinformatics and molecular biology techniques is very perspective for further studies of the evolution of tandem repeats.

Details

Language :
Russian
ISSN :
0041-3771
Volume :
57
Issue :
2
Database :
MEDLINE
Journal :
Tsitologiia
Publication Type :
Academic Journal
Accession number :
26035967