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An in-silico analysis of the effect of heart position and orientation on the ECG morphology and vectorcardiogram parameters in patients with heart failure and intraventricular conduction defects.
- Source :
-
Journal of electrocardiology [J Electrocardiol] 2015 Jul-Aug; Vol. 48 (4), pp. 617-25. Date of Electronic Publication: 2015 May 08. - Publication Year :
- 2015
-
Abstract
- Aim: The aim of this study was to investigate the influence of geometrical factors on the ECG morphology and vectorcardiogram (VCG) parameters.<br />Methods: Patient-tailored models based on five heart-failure patients with intraventricular conduction defects (IVCDs) were created. The heart was shifted up to 6 cm to the left, right, up, and down and rotated ±30° around the anteroposterior axis. Precordial electrodes were shifted 3 cm down.<br />Results: Geometry modifications strongly altered ECG notching/slurring and intrinsicoid deflection time. Maximum VCG parameter changes were small for QRS duration (-6% to +10%) and QRS-T angle (-6% to +3%), but considerable for QRS amplitude (-36% to +59%), QRS area (-37% to +42%), T-wave amplitude (-41% to +36%), and T-wave area (-42% to +33%).<br />Conclusion: The position of the heart with respect to the electrodes is an important factor determining notching/slurring and voltage-dependent parameters and therefore must be considered for accurate diagnosis of IVCDs.<br /> (Copyright © 2015 Elsevier Inc. All rights reserved.)
- Subjects :
- Aged
Arrhythmias, Cardiac complications
Arrhythmias, Cardiac diagnosis
Computer Simulation
Diagnosis, Computer-Assisted methods
Electrocardiography methods
Female
Heart Failure complications
Heart Failure diagnosis
Humans
Male
Middle Aged
Patient-Specific Modeling
Posture
Reproducibility of Results
Sensitivity and Specificity
Arrhythmias, Cardiac physiopathology
Heart Conduction System physiopathology
Heart Failure physiopathology
Models, Cardiovascular
Patient Positioning methods
Vectorcardiography methods
Subjects
Details
- Language :
- English
- ISSN :
- 1532-8430
- Volume :
- 48
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Journal of electrocardiology
- Publication Type :
- Academic Journal
- Accession number :
- 26025201
- Full Text :
- https://doi.org/10.1016/j.jelectrocard.2015.05.004