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Role of hypofractionated radiotherapy in breast locoregional radiation.
- Source :
-
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique [Cancer Radiother] 2015 Jun; Vol. 19 (4), pp. 241-7. Date of Electronic Publication: 2015 May 23. - Publication Year :
- 2015
-
Abstract
- Long-term results of randomised trials have confirmed the safety and efficacy of hypofractionated radiotherapy using approximately 2.6 Gy per fraction to lower total doses of 40-42.6 Gy delivered over 3 weeks, for postoperative treatment of early breast cancer. In these trials, hypofractionated radiotherapy was predominantly used for breast only treatment, while there are fewer trials that specifically examined hypofractionated radiotherapy to the breast plus regional nodes. Hypofractionated locoregional radiation is considered a standard of care in the United Kingdom and in some parts of Canada. We aim to review the radiobiology and normal tissue effects of hypofractionated locoregional radiation and to summarize available published clinical experiences using this treatment strategy as adjuvant therapy after breast conserving surgery or mastectomy for women with early breast cancer.<br /> (Copyright © 2015. Published by Elsevier SAS.)
Details
- Language :
- English
- ISSN :
- 1769-6658
- Volume :
- 19
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
- Publication Type :
- Academic Journal
- Accession number :
- 26004842
- Full Text :
- https://doi.org/10.1016/j.canrad.2015.02.012