K356dup--an in-frame insertion in the BCR-ABL gene in an imatinib-resistant chronic myeloid leukemia.

Subjects

Subjects :

Dasatinib therapeutic use
Drug Resistance, Neoplasm genetics
Female
Fusion Proteins, bcr-abl antagonists & inhibitors
Fusion Proteins, bcr-abl genetics
Gene Expression Regulation, Leukemic drug effects
Humans
Imatinib Mesylate chemistry
Imatinib Mesylate pharmacology
Leukemia, Myelogenous, Chronic, BCR-ABL Positive genetics
Models, Molecular
Protein Binding
Protein Kinase Inhibitors chemistry
Protein Kinase Inhibitors pharmacology
Protein Kinase Inhibitors therapeutic use
Protein Structure, Tertiary
Proto-Oncogene Proteins c-abl antagonists & inhibitors
Proto-Oncogene Proteins c-abl chemistry
Reverse Transcriptase Polymerase Chain Reaction
Young Adult
Imatinib Mesylate therapeutic use
Leukemia, Myelogenous, Chronic, BCR-ABL Positive drug therapy
Mutagenesis, Insertional
Proto-Oncogene Proteins c-abl genetics

Details

Language :

English

ISSN :

1751-553X

Volume :

34

Issue :

6

Database :

MEDLINE

Journal :

International journal of laboratory hematology

Publication Type :

Report

Accession number :

25998099

Full Text :

https://doi.org/10.1111/j.1751-553x.2012.01443.x