Case Study: Diffuse Large B-Cell Lymphoma Arising in Ovarian Mature Cystic Teratoma.

Authors :: Maguire A
Castriciano G
Walker J
Molloy K
Quinn F
Osman N
Vandenberghe E
Jeffers M
Gaffney E
Flavin R
Source :: International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists [Int J Gynecol Pathol] 2015 Sep; Vol. 34 (5), pp. 459-64.
Publication Year :: 2015
Abstract: We describe an unexpected finding of diffuse large B-cell lymphoma associated with mature cystic teratoma of the ovary. A 68-yr-old woman with a complex left ovarian cystic mass on imaging underwent bilateral salpingo-oophorectomy, lymphadenectomy, appendicectomy, and omentectomy. Histopathologic examination revealed nodules of malignant non-Hodgkin lymphoma within the teratoma. A diagnosis of diffuse large B-cell lymphoma, germinal center cell subtype by Hans criteria was made after immunostaining and molecular studies. The patient was treated with R-CHOP chemotherapy and remains disease-free at 14-mo follow-up.

Language :: English
ISSN :: 1538-7151
Volume :: 34
Issue :: 5
Database :: MEDLINE
Journal :: International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
Publication Type :: Academic Journal
Accession number :: 25996637
Full Text :: https://doi.org/10.1097/PGP.0000000000000172

Full Text Access

Tools