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Preliminary study of coconut water for graft tissues preservation in transplantation.

Authors :
César JM
Petroianu A
Vasconcelos Lde S
Cardoso VN
Mota Ld
Barbosa AJ
Soares CD
de Oliveira AL
Source :
Revista do Colegio Brasileiro de Cirurgioes [Rev Col Bras Cir] 2015 Jan-Feb; Vol. 42 (1), pp. 43-8.
Publication Year :
2015

Abstract

Objective: to verify the effectiveness of coconut water in preserving tissues for transplant.<br />Methods: Fifty male Wistar rats were randomly distributed in five groups, according to the following preservation solutions for tissue grafts: Group 1: Lactated Ringer; Group 2: Belzer solution; Group 3: mature coconut water; Group 4: green coconut water; Group 5: modified coconut water. In Group 5, the green coconut water has been modified like the Belzer solution. From each animal we harvested the spleen, ovaries and skin of the back segment. These tissues were preserved for six hours in one of the solutions. Then, the grafts were reimplanted. The recovery of the function of the implanted tissues was assessed 90 days after surgery, by splenic scintigraphy and blood exam. The implanted tissues were collected for histopathological examination.<br />Results: The serum levels did not differ among groups, except for the animals in Group 5, which showed higher levels of IgG than Group 1, and differences in relation to FSH between groups 1 and 2 (p <0.001), 4 and 2 (p = 0.03) and 5 and 2 (p = 0.01). The splenic scintigraphy was not different between groups. The ovarian tissue was better preserved in mature coconut water (p <0.007).<br />Conclusion: the coconut water-based solutions preserves spleen, ovary, and rat skin for six hours, maintaining their normal function.

Details

Language :
English; Portuguese
ISSN :
1809-4546
Volume :
42
Issue :
1
Database :
MEDLINE
Journal :
Revista do Colegio Brasileiro de Cirurgioes
Publication Type :
Academic Journal
Accession number :
25992700
Full Text :
https://doi.org/10.1590/0100-69912015001009