Administration of a maple syrup extract to mitigate their hepatic inflammation induced by a high-fat diet: a transcriptome analysis.

Authors :: Kamei A
Watanabe Y
Shinozaki F
Yasuoka A
Kondo T
Ishijima T
Toyoda T
Arai S
Abe K
Source :: Bioscience, biotechnology, and biochemistry [Biosci Biotechnol Biochem] 2015; Vol. 79 (11), pp. 1893-7. Date of Electronic Publication: 2015 May 18.
Publication Year :: 2015
Abstract: Effects of the administration of maple syrup extract (MSX) on hepatic gene expression were investigated in mice fed a high-fat diet. Gene annotation enrichment analysis based on gene ontology revealed some changes in the expression of genes related to lipid metabolism and the immune response in MSX-fed mice. Detailed analysis of these data indicated that MSX ingestion mitigates hepatic inflammation.

Subjects :: Acer chemistry
Animals
Diet, High-Fat adverse effects
Gene Expression drug effects
Inflammation pathology
Lipid Metabolism drug effects
Lipid Metabolism genetics
Liver pathology
Mice
Plant Extracts chemistry
Transcriptome drug effects
Inflammation drug therapy
Liver drug effects
Plant Extracts administration & dosage
Transcriptome genetics

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