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Health economic models in hemophilia A and utility assumptions from a clinician's perspective.
- Source :
-
Pediatric blood & cancer [Pediatr Blood Cancer] 2015 Oct; Vol. 62 (10), pp. 1826-31. Date of Electronic Publication: 2015 May 14. - Publication Year :
- 2015
-
Abstract
- Background: The clinical benefits of prophylaxis in patients with hemophilia are well-established and include the following: reduced bleeding episodes, prevention of joint damage, decreased inhibitor development, and improved health-related quality of life. However, the cost-effectiveness of prophylaxis is still not clear.<br />Procedures: We reviewed the published hemophilia prophylaxis economic models focusing on utility assumptions.<br />Results: We found six cost-utility studies that compared prophylaxis and on-demand regimens. These studies reported remarkably different results, using utility values based on different assumptions and data sources.<br />Conclusions: We suggest that cooperation among key stakeholders (clinicians, patient organizations and health-care decision makers) as a means of collecting evidence-based and experiential data to represent both the utility and the quality of life changes for patients with Hemophilia A who are treated with prophylaxis or receive on-demand treatments may represent a winning strategy with which to resolve the outstanding issues related to health technology assessments in the care of patients with hemophilia.<br /> (© 2015 Wiley Periodicals, Inc.)
Details
- Language :
- English
- ISSN :
- 1545-5017
- Volume :
- 62
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Pediatric blood & cancer
- Publication Type :
- Academic Journal
- Accession number :
- 25976056
- Full Text :
- https://doi.org/10.1002/pbc.25543