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ALK-negative anaplastic large cell lymphoma is sensitive to bortezomib through Noxa upregulation and release of Bax from Bcl-2.
- Source :
-
Haematologica [Haematologica] 2015 Sep; Vol. 100 (9), pp. e365-8. Date of Electronic Publication: 2015 May 14. - Publication Year :
- 2015
- Subjects :
- Anaplastic Lymphoma Kinase
Female
Humans
Male
Tumor Cells, Cultured
Bortezomib pharmacology
Gene Expression Regulation, Neoplastic drug effects
Lymphoma, Large-Cell, Anaplastic drug therapy
Lymphoma, Large-Cell, Anaplastic metabolism
Lymphoma, Large-Cell, Anaplastic pathology
Proto-Oncogene Proteins c-bcl-2 biosynthesis
Receptor Protein-Tyrosine Kinases
Up-Regulation drug effects
bcl-2-Associated X Protein biosynthesis
Subjects
Details
- Language :
- English
- ISSN :
- 1592-8721
- Volume :
- 100
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Haematologica
- Publication Type :
- Report
- Accession number :
- 25975837
- Full Text :
- https://doi.org/10.3324/haematol.2014.118828