Ag2 and Ag3 clusters: synthesis, characterization, and interaction with DNA.

Authors :: Buceta D
Busto N
Barone G
Leal JM
Domínguez F
Giovanetti LJ
Requejo FG
García B
López-Quintela MA
Source :: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2015 Jun 22; Vol. 54 (26), pp. 7612-6. Date of Electronic Publication: 2015 May 12.
Publication Year :: 2015
Abstract: Subnanometric samples, containing exclusively Ag2 and Ag3 clusters, were synthesized for the first time by kinetic control using an electrochemical technique without the use of surfactants or capping agents. By combination of thermodynamic and kinetic measurements and theoretical calculations, we show herein that Ag3 clusters interact with DNA through intercalation, inducing significant structural distortion to the DNA. The lifetime of Ag3 clusters in the intercalated position is two to three orders of magnitude longer than for classical organic intercalators, such as ethidium bromide or proflavine.<br /> (© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)