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Humoral immunity status if infertile men antisperm antibodies and various pathologies of reproductive organs.
- Source :
-
Georgian medical news [Georgian Med News] 2015 Apr (241), pp. 58-62. - Publication Year :
- 2015
-
Abstract
- The aim of the research was to study humoral immunity status of infertile men with high concentration of antisperm antibodies in blood plasma, sexually transmitted diseases (STD) and various pathologies of reproductive system. Analysis of 496 outpatient cards has been conducted. It was found, that patients with high levels of ASA >150 mg/l, or average 100-150 mg/l, had statistically significant (p=0,001) high content of Ig A and Ig G relative to the control group. Men with serum ASA concentration >100 mg/l, had statistically insignificant increased levels of all 3 types of immunoglobulins relative to the control group. Patients infected with Chlamydia trachomatis proved to have decreased IgA and IgG, 0,95±0,12 and 6,64±0,5 respectively (p<0,001). As for the patients infected with Ureaplasma urealyticum, decreased levels in Ig A and Ig M have been reported as 0,75±0,29 and 1,08±0,08 respectively (p<0,05). In the course of prostate gland inflammation statistically significant deficiency of Ig A and IgG was evident relative to the control group, 0,75±0,10 g/l and 5,94±0,54 g/l respectively (p<0,001). As for the males with varicocele, Ig A and Ig M decrease is noticeable relative to the control group, 1,06±0,21 g/l and 0,61±0,19 g/l respectively (p<0,05).
- Subjects :
- Adolescent
Adult
Antibodies isolation & purification
Chlamydia Infections complications
Chlamydia Infections microbiology
Chlamydia trachomatis immunology
Chlamydia trachomatis pathogenicity
Humans
Infertility, Male etiology
Infertility, Male microbiology
Male
Middle Aged
Reproduction immunology
Reproduction physiology
Sexually Transmitted Diseases complications
Sexually Transmitted Diseases microbiology
Spermatozoa immunology
Spermatozoa pathology
Ureaplasma urealyticum immunology
Ureaplasma urealyticum pathogenicity
Antibodies immunology
Immunity, Humoral
Infertility, Male immunology
Sexually Transmitted Diseases immunology
Subjects
Details
- Language :
- English
- ISSN :
- 1512-0112
- Issue :
- 241
- Database :
- MEDLINE
- Journal :
- Georgian medical news
- Publication Type :
- Academic Journal
- Accession number :
- 25953941