Back to Search
Start Over
A triple-color fluorescent probe for multiple nuclease assays.
- Source :
-
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2015 Jun 04; Vol. 51 (44), pp. 9121-4. - Publication Year :
- 2015
-
Abstract
- We develop a triple-color fluorescent probe which may function as a lab-on-a-DNA-molecule for simultaneous detection of multiple exonucleases/restriction endonucleases. This triple-color fluorescent probe can be further applied for the discrimination of seven exonucleases and four cell lines as well as the screening of various nuclease inhibitors.
- Subjects :
- 2-Aminopurine chemistry
Cell Line, Tumor
DNA Probes metabolism
DNA Restriction Enzymes metabolism
Exonucleases metabolism
Fluorescein chemistry
Fluorescent Dyes metabolism
Humans
Rhodamines chemistry
DNA Probes chemistry
DNA Restriction Enzymes chemistry
Exonucleases chemistry
Fluorescent Dyes chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1364-548X
- Volume :
- 51
- Issue :
- 44
- Database :
- MEDLINE
- Journal :
- Chemical communications (Cambridge, England)
- Publication Type :
- Academic Journal
- Accession number :
- 25940190
- Full Text :
- https://doi.org/10.1039/c5cc02177d