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Triflic acid catalyzed formal [3 + 2] cycloaddition of donor-acceptor oxiranes and nitriles: a facile access to 3-oxazolines.
- Source :
-
Organic letters [Org Lett] 2015 May 15; Vol. 17 (10), pp. 2385-7. Date of Electronic Publication: 2015 May 04. - Publication Year :
- 2015
-
Abstract
- A TfOH-catalyzed chemoselective [3 + 2] cycloaddition of donor-acceptor oxiranes and nitriles is described. This reaction provides an efficient and practical method for the preparation of useful 3-oxazolines in good to excellent yields (up to 99%).
Details
- Language :
- English
- ISSN :
- 1523-7052
- Volume :
- 17
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Organic letters
- Publication Type :
- Academic Journal
- Accession number :
- 25938163
- Full Text :
- https://doi.org/10.1021/acs.orglett.5b00911