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Use of Antiepileptic Drugs in Patients with Chronic Kidney Disease and End Stage Renal Disease.
- Source :
-
Seminars in dialysis [Semin Dial] 2015 Jul-Aug; Vol. 28 (4), pp. 404-12. Date of Electronic Publication: 2015 May 01. - Publication Year :
- 2015
-
Abstract
- Epilepsy is a disorder with an approximate worldwide prevalence of 1%. Due to complexities of metabolism, protein-binding, renal elimination, and other pharmacokinetic parameters, the dosing of antiepileptic drugs (AEDs) in patients with chronic kidney disease (CKD) or end stage renal disease (ESRD) deserves special attention. This is a review of the most commonly prescribed AEDs with special focus on their indication, pharmacokinetics, and unique considerations for use in patients with CKD and ESRD. A review of their renal toxicities is also included.<br /> (© 2015 Wiley Periodicals, Inc.)
Details
- Language :
- English
- ISSN :
- 1525-139X
- Volume :
- 28
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Seminars in dialysis
- Publication Type :
- Academic Journal
- Accession number :
- 25929593
- Full Text :
- https://doi.org/10.1111/sdi.12385