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Efficacy of three broad-spectrum anthelmintics against gastrointestinal nematode infections of goats.
- Source :
-
Veterinary parasitology [Vet Parasitol] 1989 Nov; Vol. 34 (1-2), pp. 71-5. - Publication Year :
- 1989
-
Abstract
- Groups of 10 goats, harbouring both naturally acquired and experimental infections of gastrointestinal nematodes, were drenched with either levamisole (5 mg kg-1), albendazole (3.8 mg kg-1) or parbendazole (15 mg kg-1), or remained untreated. Haemonchus contortus was the numerically dominant infection, with Strongyloides papillosus, Trichostrongylus colubriformis and Oesophagostomum columbianum also present. At 5-6 days post-treatment, goats were killed and necropsied. Post-mortem worm counts showed that the reduction in mean total worm burdens was 57.4% in levamisole-treated animals, 71.1% in the albendazole group and 85.1% in the parbendazole group. Reductions for H. contortus were 80.2, 87.9 and 83.9% in the levamisole-, albendazole- and parbendazole-treated groups, respectively. These data indicate that the anthelmintics in question are not being applied at an adequate dose rate for goats, and/or resistance to anthelmintics is occurring in the field in Pernambuco State, northeast Brazil.
- Subjects :
- Albendazole therapeutic use
Animals
Benzimidazoles therapeutic use
Brazil
Goats
Intestinal Diseases, Parasitic drug therapy
Levamisole therapeutic use
Male
Nematode Infections drug therapy
Random Allocation
Anthelmintics therapeutic use
Goat Diseases drug therapy
Intestinal Diseases, Parasitic veterinary
Nematode Infections veterinary
Subjects
Details
- Language :
- English
- ISSN :
- 0304-4017
- Volume :
- 34
- Issue :
- 1-2
- Database :
- MEDLINE
- Journal :
- Veterinary parasitology
- Publication Type :
- Academic Journal
- Accession number :
- 2588471
- Full Text :
- https://doi.org/10.1016/0304-4017(89)90166-0