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[The evaluation of oxidative stress in women with sleep disturbances in post menopause conditions using integrated indicator].
- Source :
-
Klinicheskaia laboratornaia diagnostika [Klin Lab Diagn] 2014 Dec; Vol. 59 (12), pp. 29-32. - Publication Year :
- 2014
-
Abstract
- The article presents results of individual evaluation of coefficient of oxidative stress as an integral indicator of balance of the system "lipids peroxidation-antioxidant defense" in women with sleep disturbances in post menopause conditions. The condition of the system "lipids peroxidation-antioxidant defense" was evaluated using analysis of content of substrates of oxidation of processes of lipid peroxidation with conjugated double bonds, diene conjugates, ketodienes and conjugated trienes, TBC-active products of retinol α-tokoferol, reduced and oxidized glutathione, activity of superoxiddismutase in blood. The application of coefficient of oxidative stress permitted to demonstrate differences in processes of lipids peroxidation in women with the same diagnosis and use it as a justification of individual approach under prescription of antioxidant therapy.
- Subjects :
- Female
Glutathione Disulfide blood
Humans
Lipid Peroxidation genetics
Middle Aged
Sleep Wake Disorders genetics
Sleep Wake Disorders pathology
Superoxide Dismutase blood
Vitamin A blood
alpha-Tocopherol blood
Antioxidants administration & dosage
Oxidative Stress genetics
Postmenopause blood
Sleep Wake Disorders blood
Subjects
Details
- Language :
- Russian
- ISSN :
- 0869-2084
- Volume :
- 59
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- Klinicheskaia laboratornaia diagnostika
- Publication Type :
- Academic Journal
- Accession number :
- 25872265