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The effects of geography on survival in patients with oral cavity squamous cell carcinoma.
- Source :
-
Oral oncology [Oral Oncol] 2015 Jun; Vol. 51 (6), pp. 578-85. Date of Electronic Publication: 2015 Apr 10. - Publication Year :
- 2015
-
Abstract
- Objective: To assess the survival outcomes of oral cavity squamous cell carcinoma (OCSCC) by differing geographical location.<br />Methods: Demographic, pathologic, treatment, and survival data was obtained from OCSCC patients from 1998-2010 in Alberta, Canada. 554 patients were included from 660 OCSCC patients. Overall, disease-specific, and disease-free survivals were estimated with Kaplan-Meier and Cox regression analyses. Patients were grouped by geographic locations.<br />Results: Patients from urban locations had improved overall, disease-specific, and disease-free survival compared to rural locations (p<0.05). Two and five year estimates of overall survival were significantly higher in the urban cohort at 84% and 78%, versus rural with 48% and 44%, respectively (p<0.05). Disease-specific and disease-free survival rates were also superior in the urban group (p<0.05). Diagnosis to treatment time for all 3 geographical groups was not found to be statistically significant (p>0.05).<br />Conclusion: This study shows that patients with OCSCC living in urban settings have improved survival compared to rural groups.<br /> (Copyright © 2015 Elsevier Ltd. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1879-0593
- Volume :
- 51
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Oral oncology
- Publication Type :
- Academic Journal
- Accession number :
- 25865551
- Full Text :
- https://doi.org/10.1016/j.oraloncology.2015.03.012