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Magnesium and Dialysis: The Neglected Cation.
- Source :
-
American journal of kidney diseases : the official journal of the National Kidney Foundation [Am J Kidney Dis] 2015 Sep; Vol. 66 (3), pp. 523-31. Date of Electronic Publication: 2015 Apr 09. - Publication Year :
- 2015
-
Abstract
- Disorders of magnesium homeostasis are very common in dialysis patients but have received scant attention. In this review, we address measurement of plasma magnesium, magnesium balance and the factors that affect magnesium flux during dialysis, the prevalence of hypo- and hypermagnesemia in dialysis patients, and the potential clinical significance of hypo- and hypermagnesemia in dialysis patients. Many factors can affect plasma magnesium concentration, including diet, nutritional status (including plasma albumin level), medications (such as proton pump inhibitors), and dialysis prescription. Further interventional studies to determine the effect of normalization of plasma magnesium concentration on clinical outcomes are needed. At the present time, we recommend that predialysis plasma magnesium be measured on a regular basis, with the dialysate magnesium concentration adjusted to maintain plasma magnesium concentration within the normal range.<br /> (Published by Elsevier Inc.)
- Subjects :
- Animals
Diabetic Nephropathies therapy
Hemodialysis Solutions chemistry
Homeostasis drug effects
Humans
Infusions, Intravenous
Intestinal Absorption physiology
Kidney Failure, Chronic therapy
Magnesium blood
Magnesium metabolism
Magnesium Sulfate administration & dosage
Male
Middle Aged
Nutritional Status
Peritoneal Dialysis
Proton Pump Inhibitors pharmacology
Torsades de Pointes drug therapy
Torsades de Pointes etiology
Homeostasis physiology
Kidney Failure, Chronic metabolism
Magnesium physiology
Renal Dialysis
Subjects
Details
- Language :
- English
- ISSN :
- 1523-6838
- Volume :
- 66
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- American journal of kidney diseases : the official journal of the National Kidney Foundation
- Publication Type :
- Academic Journal
- Accession number :
- 25864370
- Full Text :
- https://doi.org/10.1053/j.ajkd.2015.01.029