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CRIT-LINE: a noninvasive tool to monitor hemoglobin levels in pediatric hemodialysis patients.

Authors :
Garro R
Sutherland S
Bayes L
Alexander S
Wong C
Source :
Pediatric nephrology (Berlin, Germany) [Pediatr Nephrol] 2015 Jun; Vol. 30 (6), pp. 991-8. Date of Electronic Publication: 2015 Apr 09.
Publication Year :
2015

Abstract

Background: The national average for achieving the KDOQI-recommended hemoglobin (Hgb) target level of 11-12 g/dL is low with the current anemia management protocol of measuring Hgb levels every 2-4 weeks to guide intervention. The objective of this study was to correlate initial Hgb readings from the CRIT-LINE monitor with actual serum Hgb levels in pediatric patients on hemodialysis (HD).<br />Methods: Data were collected from pediatric HD patients who had Hgb tests ordered for routine and/or clinical reasons. Hgb concentrations were read with the CRIT-LINE after 0.5 or 1 L of blood had been processed by HD in patients with a body weight of ≤20 or >20 kg, respectively. Ultrafiltration was kept at a minimum until the CRIT-LINE Hgb was read.<br />Results: In total, 217 Hgb readings from 23 HD patients were analyzed. Results showed a statistically significant correlation between CRIT-LINE readings and laboratory Hgb measurements (r = 0.94, p < 0.0001) using Pearson correlation coefficients for well-distributed data. The mean Hgb levels measured by CRIT-LINE and the laboratory were 11.12 ± 1.63 and 11.31 ± 1.69 g/dL, respectively.<br />Conclusions: The CRIT-LINE monitor is an accurate instrument for monitoring Hgb levels in HD patients. Further studies will be needed to evaluate whether using CRIT-LINE Hgb levels to guide anemia management will improve the percentage of children with Hgb levels within target.

Details

Language :
English
ISSN :
1432-198X
Volume :
30
Issue :
6
Database :
MEDLINE
Journal :
Pediatric nephrology (Berlin, Germany)
Publication Type :
Academic Journal
Accession number :
25854612
Full Text :
https://doi.org/10.1007/s00467-014-2986-1