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[Ribosome: lessons of a molecular factory construction].

Authors :
Sergeeva OV
Sergiev PV
Bogdanov AA
Dontsova OA
Source :
Molekuliarnaia biologiia [Mol Biol (Mosk)] 2014 Jul-Aug; Vol. 48 (4), pp. 543-60.
Publication Year :
2014

Abstract

Ribosome is a macromolecular complex, which is responsible for protein biosynthesis. Two bacterial ribosomal subunits contain more than 4000 RNA nucleotides and 50 proteins. Ribosome assembly is a complicated multi-step process, vitally important for cell. In this review we summarised present-day conceptions about the mechanism of the bacterial ribosome assembly in the cell and in vitro model systems. Some details of the assembly of this machinery are still-unknown.

Details

Language :
Russian
ISSN :
0026-8984
Volume :
48
Issue :
4
Database :
MEDLINE
Journal :
Molekuliarnaia biologiia
Publication Type :
Academic Journal
Accession number :
25842841