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[Ribosome: lessons of a molecular factory construction].
- Source :
-
Molekuliarnaia biologiia [Mol Biol (Mosk)] 2014 Jul-Aug; Vol. 48 (4), pp. 543-60. - Publication Year :
- 2014
-
Abstract
- Ribosome is a macromolecular complex, which is responsible for protein biosynthesis. Two bacterial ribosomal subunits contain more than 4000 RNA nucleotides and 50 proteins. Ribosome assembly is a complicated multi-step process, vitally important for cell. In this review we summarised present-day conceptions about the mechanism of the bacterial ribosome assembly in the cell and in vitro model systems. Some details of the assembly of this machinery are still-unknown.
- Subjects :
- Escherichia coli genetics
Escherichia coli metabolism
GTP Phosphohydrolases metabolism
RNA Helicases metabolism
Ribosomal Proteins genetics
Ribosome Subunits, Large, Bacterial metabolism
Ribosome Subunits, Small, Bacterial metabolism
RNA, Ribosomal metabolism
Ribosomal Proteins metabolism
Ribosomes genetics
Ribosomes metabolism
Subjects
Details
- Language :
- Russian
- ISSN :
- 0026-8984
- Volume :
- 48
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Molekuliarnaia biologiia
- Publication Type :
- Academic Journal
- Accession number :
- 25842841