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Adjuvant hormonal therapy and fertility preservation in premenopausal breast cancer: a survey among Italian oncologists.
- Source :
-
Future oncology (London, England) [Future Oncol] 2015; Vol. 11 (8), pp. 1181-9. - Publication Year :
- 2015
-
Abstract
- Background: Increasing age of first pregnancy among Italian women with premenopausal breast cancer makes adjuvant hormonal therapy a hot topic, justifying a survey on the therapeutic approach of Italian oncologists.<br />Materials & Methods: From April to July 2012, an 11-item electronic questionnaire was submitted to Italian oncologists and 611 out of 974 invited filled questionnaires were collected from all over Italy.<br />Results: In total, 97.7% of patients aged <40 years needing only hormonal therapy would receive both tamoxifen and luteinizing hormone-releasing hormone agonists (LHRHa); 2.3% tamoxifen or LHRHa alone. For the majority of oncologists LHRHa was also the preferred choice to preserving fertility.<br />Conclusion: Results are rather consistent with major guidelines but with a greater use of LHRHa and aromatase inhibitor.
- Subjects :
- Adult
Aged
Aromatase Inhibitors administration & dosage
Attitude of Health Personnel
Chemotherapy, Adjuvant
Female
Humans
Italy
Male
Middle Aged
Practice Patterns, Physicians'
Pregnancy Tests
Premenopause
Surveys and Questionnaires
Tamoxifen administration & dosage
Antineoplastic Agents, Hormonal therapeutic use
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Breast Neoplasms therapy
Fertility Preservation
Gonadotropin-Releasing Hormone agonists
Medical Oncology
Subjects
Details
- Language :
- English
- ISSN :
- 1744-8301
- Volume :
- 11
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Future oncology (London, England)
- Publication Type :
- Academic Journal
- Accession number :
- 25832875
- Full Text :
- https://doi.org/10.2217/fon.14.289