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Adjuvant hormonal therapy and fertility preservation in premenopausal breast cancer: a survey among Italian oncologists.

Authors :
Barni S
CollovĂ  E
Frassoldati A
Amoroso D
Source :
Future oncology (London, England) [Future Oncol] 2015; Vol. 11 (8), pp. 1181-9.
Publication Year :
2015

Abstract

Background: Increasing age of first pregnancy among Italian women with premenopausal breast cancer makes adjuvant hormonal therapy a hot topic, justifying a survey on the therapeutic approach of Italian oncologists.<br />Materials & Methods: From April to July 2012, an 11-item electronic questionnaire was submitted to Italian oncologists and 611 out of 974 invited filled questionnaires were collected from all over Italy.<br />Results: In total, 97.7% of patients aged <40 years needing only hormonal therapy would receive both tamoxifen and luteinizing hormone-releasing hormone agonists (LHRHa); 2.3% tamoxifen or LHRHa alone. For the majority of oncologists LHRHa was also the preferred choice to preserving fertility.<br />Conclusion: Results are rather consistent with major guidelines but with a greater use of LHRHa and aromatase inhibitor.

Details

Language :
English
ISSN :
1744-8301
Volume :
11
Issue :
8
Database :
MEDLINE
Journal :
Future oncology (London, England)
Publication Type :
Academic Journal
Accession number :
25832875
Full Text :
https://doi.org/10.2217/fon.14.289