Back to Search
Start Over
Fiber-optic detector for real time dosimetry of a micro-planar x-ray beam.
- Source :
-
Medical physics [Med Phys] 2015 Apr; Vol. 42 (4), pp. 1966-72. - Publication Year :
- 2015
-
Abstract
- Purpose: Here, the authors describe a dosimetry measurement technique for microbeam radiation therapy using a nanoparticle-terminated fiber-optic dosimeter (nano-FOD).<br />Methods: The nano-FOD was placed in the center of a 2 cm diameter mouse phantom to measure the deep tissue dose and lateral beam profile of a planar x-ray microbeam.<br />Results: The continuous dose rate at the x-ray microbeam peak measured with the nano-FOD was 1.91 ± 0.06 cGy s(-1), a value 2.7% higher than that determined via radiochromic film measurements (1.86 ± 0.15 cGy s(-1)). The nano-FOD-determined lateral beam full-width half max value of 420 μm exceeded that measured using radiochromic film (320 μm). Due to the 8° angle of the collimated microbeam and resulting volumetric effects within the scintillator, the profile measurements reported here are estimated to achieve a resolution of ∼0.1 mm; however, for a beam angle of 0°, the theoretical resolution would approach the thickness of the scintillator (∼0.01 mm).<br />Conclusions: This work provides proof-of-concept data and demonstrates that the novel nano-FOD device can be used to perform real-time dosimetry in microbeam radiation therapy to measure the continuous dose rate at the x-ray microbeam peak as well as the lateral beam shape.
- Subjects :
- Animals
Calibration
Equipment Design
Mice
Microscopy, Electron, Scanning
Nanoparticles
Phantoms, Imaging
Radiometry methods
X-Rays
Fiber Optic Technology instrumentation
Radiometry instrumentation
Radiotherapy instrumentation
Radiotherapy methods
X-Ray Therapy instrumentation
X-Ray Therapy methods
Subjects
Details
- Language :
- English
- ISSN :
- 2473-4209
- Volume :
- 42
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Medical physics
- Publication Type :
- Academic Journal
- Accession number :
- 25832087
- Full Text :
- https://doi.org/10.1118/1.4915078