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Enhancers: holding out for the right promoter.

Authors :
Lorberbaum DS
Barolo S
Source :
Current biology : CB [Curr Biol] 2015 Mar 30; Vol. 25 (7), pp. R290-3.
Publication Year :
2015

Abstract

Some transcriptional enhancers work best with one type of promoter, while ignoring others. How widespread is such specificity across the genome? A new study finds that, in a fair fight, most enhancers prefer to activate promoters resembling those of their parent genes.<br /> (Copyright © 2015 Elsevier Ltd. All rights reserved.)

Details

Language :
English
ISSN :
1879-0445
Volume :
25
Issue :
7
Database :
MEDLINE
Journal :
Current biology : CB
Publication Type :
Academic Journal
Accession number :
25829016
Full Text :
https://doi.org/10.1016/j.cub.2015.01.039