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Convenient access to polyfunctional pyrazoles via a highly efficient and regioselective multicomponent reaction.
- Source :
-
Organic letters [Org Lett] 2015 Apr 17; Vol. 17 (8), pp. 1914-7. Date of Electronic Publication: 2015 Mar 31. - Publication Year :
- 2015
-
Abstract
- A multicomponent reaction has been developed for the synthesis of polyfunctional pyrazole derivatives from readily available arylglyoxal monohydrates, tosylhydrazine, and aldehydes or ketones. This synthetic method has significant advantages in broad substrate scope, excellent regioselectivity, and simple operation.
Details
- Language :
- English
- ISSN :
- 1523-7052
- Volume :
- 17
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Organic letters
- Publication Type :
- Academic Journal
- Accession number :
- 25826709
- Full Text :
- https://doi.org/10.1021/acs.orglett.5b00605