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Anatomical confirmation of computed tomography-based diagnosis of the atherosclerosis discovered in 17th century Korean mummy.
- Source :
-
PloS one [PLoS One] 2015 Mar 27; Vol. 10 (3), pp. e0119474. Date of Electronic Publication: 2015 Mar 27 (Print Publication: 2015). - Publication Year :
- 2015
-
Abstract
- In the present study on a newly discovered 17th century Korean mummy, computed tomography (CT) revealed multiple aortic calcifications within the aortic wall that were indicative of ancient atherosclerosis. The CT-based findings were confirmed by our subsequent post-factum dissection, which exhibited possible signs of the disease including ulcerated plaques, ruptured hemorrhages, and intimal thickening where the necrotic core was covered by the fibrous cap. These findings are strong indicators that the mummy suffered from aortic atherosclerosis during her lifetime. The present study is a good example of how CT images of vascular calcifications can be a useful diagnostic tool in forming at least preliminary diagnoses of ancient atherosclerosis.
- Subjects :
- Abdominal Cavity diagnostic imaging
Abdominal Cavity pathology
Adult
Aorta, Abdominal diagnostic imaging
Aorta, Abdominal pathology
Coronary Vessels diagnostic imaging
Coronary Vessels pathology
Female
Heart diagnostic imaging
Humans
Middle Aged
Asian People
Atherosclerosis diagnostic imaging
Atherosclerosis pathology
Mummies diagnostic imaging
Mummies pathology
Tomography, X-Ray Computed
Subjects
Details
- Language :
- English
- ISSN :
- 1932-6203
- Volume :
- 10
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- PloS one
- Publication Type :
- Academic Journal
- Accession number :
- 25816014
- Full Text :
- https://doi.org/10.1371/journal.pone.0119474