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Global migration of influenza A viruses in swine.
- Source :
-
Nature communications [Nat Commun] 2015 Mar 27; Vol. 6, pp. 6696. Date of Electronic Publication: 2015 Mar 27. - Publication Year :
- 2015
-
Abstract
- The complex and unresolved evolutionary origins of the 2009 H1N1 influenza pandemic exposed major gaps in our knowledge of the global spatial ecology and evolution of influenza A viruses in swine (swIAVs). Here we undertake an expansive phylogenetic analysis of swIAV sequence data and demonstrate that the global live swine trade strongly predicts the spatial dissemination of swIAVs, with Europe and North America acting as sources of viruses in Asian countries. In contrast, China has the world's largest swine population but is not a major exporter of live swine, and is not an important source of swIAVs in neighbouring Asian countries or globally. A meta-population simulation model incorporating trade data predicts that the global ecology of swIAVs is more complex than previously thought, and the United States and China's large swine populations are unlikely to be representative of swIAV diversity in their respective geographic regions, requiring independent surveillance efforts throughout Latin America and Asia.
- Subjects :
- Animals
Asia
Base Sequence
Canada
China
Commerce
Europe
Internationality
Latin America
Mexico
Molecular Epidemiology
Molecular Sequence Data
North America
Orthomyxoviridae Infections epidemiology
Orthomyxoviridae Infections virology
Swine Diseases epidemiology
United States
Influenza A virus genetics
Orthomyxoviridae Infections veterinary
RNA, Viral genetics
Swine virology
Swine Diseases virology
Subjects
Details
- Language :
- English
- ISSN :
- 2041-1723
- Volume :
- 6
- Database :
- MEDLINE
- Journal :
- Nature communications
- Publication Type :
- Academic Journal
- Accession number :
- 25813399
- Full Text :
- https://doi.org/10.1038/ncomms7696