NPM1 mutations may reveal acute myeloid leukemia in cases otherwise morphologically diagnosed as myelodysplastic syndromes or myelodysplastic/myeloproliferative neoplasms.

Authors :: Forghieri F
Paolini A
Morselli M
Bigliardi S
Bonacorsi G
Leonardi G
Coluccio V
Maccaferri M
Fantuzzi V
Faglioni L
Colaci E
Soci F
Nasillo V
Messerotti A
Arletti L
Pioli V
Zucchini P
Quadrelli C
Corradini G
Giacobbi F
Vallerini D
Riva G
Barozzi P
Lagreca I
Marasca R
Narni F
Mecucci C
Ottaviani E
Martinelli G
Falini B
Luppi M
Potenza L
Source :: Leukemia & lymphoma [Leuk Lymphoma] 2015; Vol. 56 (11), pp. 3222-6. Date of Electronic Publication: 2015 May 12.
Publication Year :: 2015

Subjects :: Aged
Biopsy
Bone Marrow pathology
Cell Transformation, Neoplastic genetics
DNA Mutational Analysis
Female
Humans
Leukemia, Myeloid, Acute diagnosis
Male
Middle Aged
Myelodysplastic Syndromes diagnosis
Myeloproliferative Disorders diagnosis
Nucleophosmin
Leukemia, Myeloid, Acute genetics
Mutation
Myelodysplastic Syndromes genetics
Myeloproliferative Disorders genetics
Nuclear Proteins genetics

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