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Rapid, simple and inexpensive production of custom 3D printed equipment for large-volume fluorescence microscopy.
- Source :
-
International journal of pharmaceutics [Int J Pharm] 2015 Oct 30; Vol. 494 (2), pp. 651-656. Date of Electronic Publication: 2015 Mar 20. - Publication Year :
- 2015
-
Abstract
- The cost of 3D printing has reduced dramatically over the last few years and is now within reach of many scientific laboratories. This work presents an example of how 3D printing can be applied to the development of custom laboratory equipment that is specifically adapted for use with the novel brain tissue clearing technique, CLARITY. A simple, freely available online software tool was used, along with consumer-grade equipment, to produce a brain slicing chamber and a combined antibody staining and imaging chamber. Using standard 3D printers we were able to produce research-grade parts in an iterative manner at a fraction of the cost of commercial equipment. 3D printing provides a reproducible, flexible, simple and cost-effective method for researchers to produce the equipment needed to quickly adopt new methods.<br /> (Copyright © 2015 The Authors. Published by Elsevier B.V. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1873-3476
- Volume :
- 494
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- International journal of pharmaceutics
- Publication Type :
- Academic Journal
- Accession number :
- 25797056
- Full Text :
- https://doi.org/10.1016/j.ijpharm.2015.03.042