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A ratiometric fluorescent probe for in situ quantification of basal mitochondrial hypochlorite in cancer cells.

Authors :
Hou JT
Li K
Yang J
Yu KK
Liao YX
Ran YZ
Liu YH
Zhou XD
Yu XQ
Source :
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2015 Apr 21; Vol. 51 (31), pp. 6781-4.
Publication Year :
2015

Abstract

A ratiometric fluorescent probe () for ClO(-) based on the conjugate of coumarin-rhodamine was presented, which could sense ClO(-) with fast response (within 5 s), high sensitivity and excellent selectivity. More importantly, is the first mitochondria-targeted ratiometric fluorescent probe to image exogenous and endogenous ClO(-).

Details

Language :
English
ISSN :
1364-548X
Volume :
51
Issue :
31
Database :
MEDLINE
Journal :
Chemical communications (Cambridge, England)
Publication Type :
Academic Journal
Accession number :
25785927
Full Text :
https://doi.org/10.1039/c5cc01217a