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Synthesis, structural and antioxidant studies of some novel N-ethyl phthalimide esters.

Authors :
Chidan Kumar CS
Loh WS
Chandraju S
Win YF
Tan WK
Quah CK
Fun HK
Source :
PloS one [PLoS One] 2015 Mar 05; Vol. 10 (3), pp. e0119440. Date of Electronic Publication: 2015 Mar 05 (Print Publication: 2015).
Publication Year :
2015

Abstract

A series of N-ethyl phthalimide esters 4(a-n) were synthesized and characterized by spectroscopic studies. Further, the molecular structure of majority of compounds were analysed by single crystal X-ray diffraction studies. The X-ray analysis revealed the importance of substituents on the crystal stability and molecular packing. All the synthesized compounds were tested for in vitro antioxidant activity by DPPH radical scavenging, FRAP and CUPRAC methods. Few of them have shown good antioxidant activity.

Details

Language :
English
ISSN :
1932-6203
Volume :
10
Issue :
3
Database :
MEDLINE
Journal :
PloS one
Publication Type :
Academic Journal
Accession number :
25742494
Full Text :
https://doi.org/10.1371/journal.pone.0119440