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Synthesis, structural and antioxidant studies of some novel N-ethyl phthalimide esters.
- Source :
-
PloS one [PLoS One] 2015 Mar 05; Vol. 10 (3), pp. e0119440. Date of Electronic Publication: 2015 Mar 05 (Print Publication: 2015). - Publication Year :
- 2015
-
Abstract
- A series of N-ethyl phthalimide esters 4(a-n) were synthesized and characterized by spectroscopic studies. Further, the molecular structure of majority of compounds were analysed by single crystal X-ray diffraction studies. The X-ray analysis revealed the importance of substituents on the crystal stability and molecular packing. All the synthesized compounds were tested for in vitro antioxidant activity by DPPH radical scavenging, FRAP and CUPRAC methods. Few of them have shown good antioxidant activity.
- Subjects :
- Antioxidants chemistry
Antioxidants pharmacology
Esters chemistry
Esters pharmacology
Free Radical Scavengers chemistry
Molecular Structure
Oxidation-Reduction
Phthalimides chemistry
Phthalimides pharmacology
X-Ray Diffraction
Antioxidants chemical synthesis
Esters chemical synthesis
Phthalimides chemical synthesis
Subjects
Details
- Language :
- English
- ISSN :
- 1932-6203
- Volume :
- 10
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- PloS one
- Publication Type :
- Academic Journal
- Accession number :
- 25742494
- Full Text :
- https://doi.org/10.1371/journal.pone.0119440