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[A case of gastric cancer with liver metastases achieving a clinical complete response after S-1 plus CDDP therapy].

Authors :
Kumazu Y
Aoyama T
Yamada T
Wada H
Kitani Y
Yamamoto N
Yukawa N
Yoshikawa T
Rino Y
Ozawa Y
Masuda M
Source :
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 2014 Nov; Vol. 41 (12), pp. 2337-9.
Publication Year :
2014

Abstract

We report a case of gastric carcinoma with metastasis to the liver responding to surgery and chemotherapy.The patient was a 74-year-old man with gastric cancer, clinically diagnosed as P0H0M0T3N0.We initially planned to perform an open distal gastrectomy.However, intraoperative findings revealed metastatic tumors in the liver.Therefore, the patient underwent a D1 distal gastrectomy.After surgery, the patient received the following chemotherapy regimens: 1 course of S-1 and 8 courses of a S-1 and cisplatin (CDDP) combination.After 8 courses of S-1 plus CDDP treatment, liver metastases could not be detected by computed tomography (CT), magnetic resonance imaging (MRI), or positron emission tomography (PET). The patient was assessed to have a clinical complete response.Fifty months after surgery, the patient is alive without recurrence.

Details

Language :
Japanese
ISSN :
0385-0684
Volume :
41
Issue :
12
Database :
MEDLINE
Journal :
Gan to kagaku ryoho. Cancer & chemotherapy
Publication Type :
Academic Journal
Accession number :
25731515