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[A case of gastric cancer with liver metastases achieving a clinical complete response after S-1 plus CDDP therapy].
- Source :
-
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 2014 Nov; Vol. 41 (12), pp. 2337-9. - Publication Year :
- 2014
-
Abstract
- We report a case of gastric carcinoma with metastasis to the liver responding to surgery and chemotherapy.The patient was a 74-year-old man with gastric cancer, clinically diagnosed as P0H0M0T3N0.We initially planned to perform an open distal gastrectomy.However, intraoperative findings revealed metastatic tumors in the liver.Therefore, the patient underwent a D1 distal gastrectomy.After surgery, the patient received the following chemotherapy regimens: 1 course of S-1 and 8 courses of a S-1 and cisplatin (CDDP) combination.After 8 courses of S-1 plus CDDP treatment, liver metastases could not be detected by computed tomography (CT), magnetic resonance imaging (MRI), or positron emission tomography (PET). The patient was assessed to have a clinical complete response.Fifty months after surgery, the patient is alive without recurrence.
- Subjects :
- Aged
Cisplatin administration & dosage
Combined Modality Therapy
Drug Combinations
Humans
Liver Neoplasms secondary
Magnetic Resonance Imaging
Male
Multimodal Imaging
Oxonic Acid administration & dosage
Positron-Emission Tomography
Remission Induction
Stomach Neoplasms pathology
Stomach Neoplasms surgery
Tegafur administration & dosage
Tomography, X-Ray Computed
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Liver Neoplasms drug therapy
Stomach Neoplasms drug therapy
Subjects
Details
- Language :
- Japanese
- ISSN :
- 0385-0684
- Volume :
- 41
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- Gan to kagaku ryoho. Cancer & chemotherapy
- Publication Type :
- Academic Journal
- Accession number :
- 25731515