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[Renoprotective effects of statins under the conditions of acute renal failure, caused by rhabdomyolysis].
- Source :
-
Biofizika [Biofizika] 2014 Sep-Oct; Vol. 59 (5), pp. 1027-30. - Publication Year :
- 2014
-
Abstract
- The experiment on white rats was targeted at the examination of influence of statins (atorvastatin, lovastatin, simvastatin) under the conditions of acute renal failure, caused by rhabdomyolysis. Renoprotective effects of statins were demonstrated by reduction of hyperazotemia and proteinuria and improvement of renal excretory function, which correlated with antioxidant properties of drugs.
- Subjects :
- Acute Kidney Injury etiology
Acute Kidney Injury urine
Animals
Male
Proteinuria drug therapy
Proteinuria etiology
Proteinuria urine
Rats
Rhabdomyolysis complications
Rhabdomyolysis urine
Acute Kidney Injury drug therapy
Hydroxymethylglutaryl-CoA Reductase Inhibitors pharmacokinetics
Kidney metabolism
Recovery of Function
Rhabdomyolysis drug therapy
Subjects
Details
- Language :
- Russian
- ISSN :
- 0006-3029
- Volume :
- 59
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Biofizika
- Publication Type :
- Academic Journal
- Accession number :
- 25730990