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[Electrophysiological mechanisms of heart rate stability of the hibernating mammals during hypothermia].
- Source :
-
Uspekhi fiziologicheskikh nauk [Usp Fiziol Nauk] 2014 Jan-Mar; Vol. 45 (1), pp. 3-26. - Publication Year :
- 2014
-
Abstract
- Despite more than 100 years of study, the mechanisms of natural resistance of the hibernator heart to cardiac arrhythmias during hypothermia has remained unknown. Renewed optimism in this area of research comes with recent methodological advances which enable to shed light on the hidden secrets of the hibernator's heart. This review discusses basic mechanisms of hypothermic ventricular arrhythmias and highlights some recent findings from the hibernator's heart electrophysiology, which may have an antiarrhythmic potential for the human heart as well.
- Subjects :
- Adaptation, Physiological
Animals
Calcium metabolism
Chlorine metabolism
Cold Temperature
Electrophysiological Phenomena
Heart innervation
Ion Channels metabolism
Myocardium metabolism
Potassium metabolism
Seasons
Heart Rate physiology
Hibernation physiology
Hypothermia physiopathology
Myocardial Contraction physiology
Subjects
Details
- Language :
- Russian
- ISSN :
- 0301-1798
- Volume :
- 45
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Uspekhi fiziologicheskikh nauk
- Publication Type :
- Academic Journal
- Accession number :
- 25702450