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Action of rimantadine on the structure of influenza A virus haemagglutinin.
- Source :
-
Acta virologica [Acta Virol] 1989 Mar; Vol. 33 (2), pp. 131-6. - Publication Year :
- 1989
-
Abstract
- Rimantadine prevents the conformational changes of influenza virus haemagglutinin (HA) caused by acid pH and the acquisition of sensitivity to trypsin, protects the haemolytic activity from inactivation and prevents the morphological changes of HA spikes on the virus surface.
- Subjects :
- Animals
Chick Embryo
Hemagglutinin Glycoproteins, Influenza Virus
Hydrogen-Ion Concentration
Influenza A virus immunology
Influenza A virus physiology
Protein Conformation drug effects
Trypsin
Virion drug effects
Virion ultrastructure
Adamantane analogs & derivatives
Hemagglutinins, Viral analysis
Influenza A virus drug effects
Membrane Fusion drug effects
Rimantadine pharmacology
Subjects
Details
- Language :
- English
- ISSN :
- 0001-723X
- Volume :
- 33
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Acta virologica
- Publication Type :
- Academic Journal
- Accession number :
- 2569808