Evidence-based decision-making 5: Translational research.

The delay in turning research into practice for the benefit of patient care has been compared to a "leaky pipeline." In the early 2000s, this delay raised concerns among governmental agencies and other sponsors of health services in many countries. Facilitating the translation of basic and clinical research into clinical practice through evidence-based decision-making and improving population health is now a major goal of health research investment agencies. Translational research or knowledge translation has emerged to bridge the gaps between basic and clinical research, and between clinical research and clinical practice. Various frameworks and definitions of translational research are presented. We present an example of an Integrated Knowledge Translation Team in Bariatric Care, and explain how an integrated knowledge translation (iKT) approach was created at the program's inception. This led to evidence-based decision-making and subsequent practice change in one area of the health care system. Real-world successes and challenges in moving research to practice are discussed.