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Cause of death in HIV-infected patients in South Carolina (2005-2013).
- Source :
-
International journal of STD & AIDS [Int J STD AIDS] 2016 Jan; Vol. 27 (1), pp. 25-32. Date of Electronic Publication: 2015 Feb 17. - Publication Year :
- 2016
-
Abstract
- The life span of persons with HIV has been greatly extended over the past 30 years due to novel therapies. In the developed world and urban settings, this results in a lifespan rivaling the lifespan of a person without HIV. A retrospective study was conducted on 459 patients of an urban, academic medical center who died between 2005 and 2013 in a medium-sized US city. Using the established Cause of Death Project (CoDe) protocol, we measured multiple factors including comorbidities, risk behaviours, contributing and underlying causes of death. This study is one of the few US-based studies using this validated protocol. Among the deaths, 25.9% were sudden and 15.2% were unexpected. Almost one-fifth were related to AIDS-related infections; 47.5% related to non-AIDS causes; with the remainder unknown. Statistically significant increases in CD4 counts and decreasing viral loads were observed over the study period. There were no statistically significant differences observed by HIV risk behaviour, race, gender, age at death, or on antiretrovirals at death. In support of the existing literature, improved HIV management appears to reduce the AIDS-related attributable death among patients observed in this study.<br /> (© The Author(s) 2015.)
- Subjects :
- AIDS-Related Opportunistic Infections epidemiology
Academic Medical Centers
Adult
Anti-HIV Agents therapeutic use
Antiretroviral Therapy, Highly Active
CD4 Lymphocyte Count
Comorbidity
Female
HIV Infections drug therapy
Humans
Male
Medical Records
Middle Aged
Population Surveillance
Retrospective Studies
Risk Factors
Risk-Taking
Sex Factors
Socioeconomic Factors
South Carolina epidemiology
Substance Abuse, Intravenous
Survival Analysis
Urban Population
Cause of Death
HIV Infections mortality
Subjects
Details
- Language :
- English
- ISSN :
- 1758-1052
- Volume :
- 27
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- International journal of STD & AIDS
- Publication Type :
- Academic Journal
- Accession number :
- 25691444
- Full Text :
- https://doi.org/10.1177/0956462415571970