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Palladium(II)-catalysed ortho-arylation of N-benzylpiperidines.
- Source :
-
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2015 Mar 14; Vol. 51 (21), pp. 4406-9. - Publication Year :
- 2015
-
Abstract
- Pd(II)-catalysed ortho-arylation of benzylic heterocycles with arylboronic acid pinacol esters (Ar-BPin) via directed C-H bond activation to generate the desired biaryl products is reported. This methodology is efficient and applicable to a wide range of functionalised Ar-BPin and benzylic heterocycles, allowing the direct synthesis of important biaryl motifs in modest to good yield.
Details
- Language :
- English
- ISSN :
- 1364-548X
- Volume :
- 51
- Issue :
- 21
- Database :
- MEDLINE
- Journal :
- Chemical communications (Cambridge, England)
- Publication Type :
- Academic Journal
- Accession number :
- 25679348
- Full Text :
- https://doi.org/10.1039/c5cc00410a