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Is it practical and cost effective to detect differentiated thyroid carcinoma metastases by (18)F-FDG PET/CT, by (18)F-FDG SPET/CT or by (131)I SPET/CT?
- Source :
-
Hellenic journal of nuclear medicine [Hell J Nucl Med] 2015 Jan-Apr; Vol. 18 (1), pp. 2-4. Date of Electronic Publication: 2015 Feb 13. - Publication Year :
- 2015
-
Abstract
- Fluorine-18-labeled 2-fluoro-2-deoxy-D-glucose positron emission tomography/computerized tomography ((18)F-FDG PET/CT) plays an important role in detecting differentiated thyroid carcinoma (DTC) metastases with elevated thyroglobulin (Tg) and negative radioiodine ((131)I) uptake. In conclusion, (18)F-FDG PET/CT may fail to detect all DTC metastases, while (131)I WBS combined with (131)I SPET/CT may be a better cheaper and diagnostic tool as suggested by the case we presented here. Positive metastases in both (131)I and (18)F-FDG SPET/CT may indicate worse prognosis. Future research may add more evidence as to which is the best diagnostic imaging modality and relate it to the molecular mechanism of the uptake of the radionuclide used.
- Subjects :
- Adult
Bone Neoplasms diagnostic imaging
Humans
Lung Neoplasms radiotherapy
Lung Neoplasms secondary
Male
Neoplasm Metastasis
Prognosis
Whole Body Imaging
Fluorodeoxyglucose F18
Iodine Radioisotopes
Multimodal Imaging
Positron-Emission Tomography
Thyroid Neoplasms diagnostic imaging
Tomography, Emission-Computed, Single-Photon
Tomography, X-Ray Computed
Subjects
Details
- Language :
- English
- ISSN :
- 1790-5427
- Volume :
- 18
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Hellenic journal of nuclear medicine
- Publication Type :
- Report
- Accession number :
- 25679071
- Full Text :
- https://doi.org/10.1967/s0024499100160