The role of positron emission tomography/computed tomography in planning radiotherapy in endometrial cancer.

Authors :: Simcock B
Narayan K
Drummond E
Bernshaw D
Wells E
Hicks RJ
Source :: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society [Int J Gynecol Cancer] 2015 May; Vol. 25 (4), pp. 645-9.
Publication Year :: 2015
Abstract: Objective: The optimal method of assessing disease distribution in endometrial cancer is widely debated. Knowledge of disease distribution assists in planning adjuvant radiotherapy; in this study we used positron emission tomography/computed tomography (PET/CT) to assess disease distribution before radiotherapy.<br />Methods: Seventy-three consecutive patients referred to the Peter MacCallum Cancer Centre for adjuvant radiotherapy for endometrial cancer, with either high-risk disease after a hysterectomy or recurrent disease, had a PET/CT before treatment. The findings on PET/CT and clinical course were recorded.<br />Results: PET/CT found additional disease in 35% of postoperative patients, changing planned treatment in 31%. In the group with known recurrence, additional disease was found in 72%, changing management in 36%.<br />Conclusions: PET/CT is a valuable tool for planning radiotherapy in endometrial cancer.

Language :: English
ISSN :: 1525-1438
Volume :: 25
Issue :: 4
Database :: MEDLINE
Journal :: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
Publication Type :: Academic Journal
Accession number :: 25675040
Full Text :: https://doi.org/10.1097/IGC.0000000000000393

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