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Voltammetric profiling of redox-active metabolites expressed by Pseudomonas aeruginosa for diagnostic purposes.

Authors :
Seviour T
Doyle LE
Lauw SJ
Hinks J
Rice SA
Nesatyy VJ
Webster RD
Kjelleberg S
Marsili E
Source :
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2015 Mar 04; Vol. 51 (18), pp. 3789-92.
Publication Year :
2015

Abstract

In Pseudomonas aeruginosa, chemical deconvolution of the pyocyanin voltammetric signal allows its expression to be observed simultaneously with the quorum sensing molecule Pseudomonas quinolone signal (PQS). Such analysis has revealed that PQS might protect pyocyanin from self-oxidation, but also exert a pro-oxidative effect on pyocyanin under oxidative conditions to produce additional redox metabolites.

Details

Language :
English
ISSN :
1364-548X
Volume :
51
Issue :
18
Database :
MEDLINE
Journal :
Chemical communications (Cambridge, England)
Publication Type :
Academic Journal
Accession number :
25650009
Full Text :
https://doi.org/10.1039/c4cc08590f