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Molecular detection of a putatively novel cyprinid herpesvirus in sichel (Pelecus cultratus) during a mass mortality event in Hungary.
- Source :
-
Archives of virology [Arch Virol] 2015 May; Vol. 160 (5), pp. 1279-83. Date of Electronic Publication: 2015 Feb 04. - Publication Year :
- 2015
-
Abstract
- In the early summer of 2014, mass mortality of sichel (Pelecus cultratus) was observed in Lake Balaton, Hungary. Histological examination revealed degenerative changes within the tubular epithelium, mainly in the distal tubules and collecting ducts in the kidneys and multifocal vacuolisation in the brain stem and cerebellum. Routine molecular investigations showed the presence of the DNA of an unknown alloherpesvirus in some specimens. Subsequently, three genes of the putative herpesviral genome (DNA polymerase, terminase, and helicase) were amplified and partially sequenced. A phylogenetic tree reconstruction based on the concatenated sequence of these three conserved genes implied that the virus belongs to the genus Cyprinivirus within the family Alloherpesviridae. The sequences of the sichel herpesvirus differ markedly from those of the cypriniviruses CyHV-1, CyHV-2 and CyHV-3, putatively representing a fifth species in the genus.
- Subjects :
- Animal Structures virology
Animals
Cluster Analysis
DNA, Viral chemistry
DNA, Viral genetics
Fish Diseases mortality
Fish Diseases pathology
Herpesviridae genetics
Herpesviridae Infections epidemiology
Herpesviridae Infections mortality
Herpesviridae Infections pathology
Histocytochemistry
Hungary epidemiology
Microscopy
Molecular Sequence Data
Phylogeny
Sequence Analysis, DNA
Sequence Homology
Viral Proteins genetics
Cyprinidae virology
Fish Diseases epidemiology
Fish Diseases virology
Herpesviridae classification
Herpesviridae isolation & purification
Herpesviridae Infections veterinary
Subjects
Details
- Language :
- English
- ISSN :
- 1432-8798
- Volume :
- 160
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Archives of virology
- Publication Type :
- Academic Journal
- Accession number :
- 25643818
- Full Text :
- https://doi.org/10.1007/s00705-015-2348-8