Systems biology of polycystic kidney disease: a critical review.

Authors :: Menezes LF
Germino GG
Source :: Wiley interdisciplinary reviews. Systems biology and medicine [Wiley Interdiscip Rev Syst Biol Med] 2015 Jan-Feb; Vol. 7 (1), pp. 39-52. Date of Electronic Publication: 2015 Feb 02.
Publication Year :: 2015
Abstract: The proliferation and diminishing costs of 'omics' approaches have finally opened the doors for small and medium laboratories to enter the 'systems biology era'. This is a welcome evolution that requires a new framework to design, interpret, and validate studies. Here, we highlight some of the challenges, contributions, and prospects of the 'cyst-ems biology' of polycystic kidney disease.<br /> (Published 2015. This article is a U.S. Government work and is in the public domain in the USA.)