Back to Search
Start Over
The potential impact of mouse model selection in preclinical evaluation of cancer immunotherapy.
- Source :
-
Oncoimmunology [Oncoimmunology] 2014 Jul 03; Vol. 3 (7), pp. e946361. Date of Electronic Publication: 2014 Jul 03 (Print Publication: 2014). - Publication Year :
- 2014
-
Abstract
- This commentary provides the authors' perspective on the article "Routes of delivery for CpG and anti-CD137 for the treatment of orthotopic kidney tumors in mice", published in PLoS ONE. It also discusses the caveats of using subcutaneous tumors to model the treatment of human cancers versus orthotopic mouse models that more closely mimic human disease.
Details
- Language :
- English
- ISSN :
- 2162-4011
- Volume :
- 3
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Oncoimmunology
- Publication Type :
- Academic Journal
- Accession number :
- 25610731
- Full Text :
- https://doi.org/10.4161/21624011.2014.946361