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Role of the kidney in the fetal programming of adult cardiovascular disease: an update.
- Source :
-
Current opinion in pharmacology [Curr Opin Pharmacol] 2015 Apr; Vol. 21, pp. 53-9. Date of Electronic Publication: 2015 Jan 12. - Publication Year :
- 2015
-
Abstract
- It is well established that an adverse in utero environment can impinge upon fetal development and place the offspring on a track leading to future cardiovascular disease. Significantly, this may occur in the absence of any outward manifestations at birth. In this brief review, we focus on potential renal mechanisms that lead to adaptations in glomerular and tubular function that initiate hypertension of developmental origin and examine potential therapeutic interventions. This report updates recent data in this field.<br /> (Crown Copyright © 2014. Published by Elsevier Ltd. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1471-4973
- Volume :
- 21
- Database :
- MEDLINE
- Journal :
- Current opinion in pharmacology
- Publication Type :
- Academic Journal
- Accession number :
- 25588322
- Full Text :
- https://doi.org/10.1016/j.coph.2014.12.010