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Spontaneous mutual ordering of nucleic acids and proteins.
- Source :
-
Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life [Orig Life Evol Biosph] 2014 Dec; Vol. 44 (4), pp. 293-8. Date of Electronic Publication: 2015 Jan 14. - Publication Year :
- 2014
-
Abstract
- It is proposed that the prebiotic ordering of nucleic acid and peptide sequences was a cooperative process in which nearly random populations of both kinds of polymers went through a codependent series of self-organisation events that simultaneously refined not only the accuracy of genetic replication and coding but also the functional specificity of protein catalysts, especially nascent aminoacyl-tRNA synthetase "urzymes".
- Subjects :
- Amino Acid Sequence
Amino Acids metabolism
Amino Acyl-tRNA Synthetases metabolism
Biocatalysis
Energy Transfer
Genetic Code
Information Theory
Molecular Sequence Data
RNA, Catalytic chemistry
RNA, Catalytic metabolism
RNA, Messenger metabolism
RNA, Transfer, Amino Acid-Specific metabolism
Thermodynamics
Amino Acids chemistry
Amino Acyl-tRNA Synthetases chemistry
Origin of Life
Protein Biosynthesis
RNA, Messenger chemistry
RNA, Transfer, Amino Acid-Specific chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1573-0875
- Volume :
- 44
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life
- Publication Type :
- Academic Journal
- Accession number :
- 25585807
- Full Text :
- https://doi.org/10.1007/s11084-014-9396-z