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Regulating the timing of CENP-A nucleosome assembly by phosphorylation.
- Source :
-
Developmental cell [Dev Cell] 2015 Jan 12; Vol. 32 (1), pp. 1-2. - Publication Year :
- 2015
-
Abstract
- In this issue of Developmental Cell, Yu et al. (2015) demonstrate that CENP-A phosphorylation by CDK1 inhibits its association with the chaperone protein HJURP and that the removal of this modification at mitotic exit is a key regulatory event that controls the timing of new CENP-A nucleosome formation at centromeres.<br /> (Copyright © 2015 Elsevier Inc. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1878-1551
- Volume :
- 32
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Developmental cell
- Publication Type :
- Academic Journal
- Accession number :
- 25584791
- Full Text :
- https://doi.org/10.1016/j.devcel.2014.12.020