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Opioid substitution therapy is associated with increased detection of hepatitis C virus infection: a 15-year observational cohort study.
- Source :
-
Drug and alcohol dependence [Drug Alcohol Depend] 2015 Mar 01; Vol. 148, pp. 213-6. Date of Electronic Publication: 2015 Jan 05. - Publication Year :
- 2015
-
Abstract
- Background: Strategies are needed to enhance screening of hepatitis C virus (HCV) infection among people who inject drugs to improve engagement in HCV treatment, and stem the growing burden of HCV-related morbidity and mortality.<br />Methods: We linked routinely collected data on enrolment in opioid substitution therapy (OST) and HCV notifications. We calculated rates of incident HCV notifications, and compared rates in and out of OST.<br />Results: Following adjustment for sex, age and calendar period, rates of incident HCV notification were significantly higher during periods of OST, compared to periods out of OST (adjusted incident rate ratio: 1.91; 95% confidence interval: 1.86, 1.97). This effect was seen across multiple treatment periods.<br />Conclusions: HCV screening in OST settings increases detection of HCV infection among people who inject drugs.<br /> (Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1879-0046
- Volume :
- 148
- Database :
- MEDLINE
- Journal :
- Drug and alcohol dependence
- Publication Type :
- Academic Journal
- Accession number :
- 25578251
- Full Text :
- https://doi.org/10.1016/j.drugalcdep.2014.12.027